"Principal Krupp once again turns into the superhero Captain Underpants in order to save the world, and Jerome Horwitz Elementary School, from the evil talking toilets and the Turbo Toilet 2000"-cProvided by publisher.

George and Harold and their doubles, Yesterday George and Yesterday Harold, have been taking turns going to school, but when the doubles fall prey to their gym teacher, Mr. Meaner, and his method of mind control that turns students into attentive, obedient, perfect children, it is up to original George and Harold to strike back. Jorge, Berto y sus dobles, Jorge y Berto de Ayer, la están pasando muy bien. Dos de ellos van a la escuela mientras los...

"La última vez que vimos a nuestros héroes, Jorge y Berto, habían sido convertidos en zombis destinados a deambular por toda la eternidad en un planeta postapocalíptico. Pero, te preguntarás, ¿por qué razón el Capitán Calzoncillos no salvó a los chicos de ese cruel destino? Para empezar, ¡el profesor Cacapipí y sus alocados viajes en el tiempo impidieron que Jorge y Berto crearan al Capitán Calzoncillos! Ahora, habiendo cambiado el curso...

George, Harold, Captain Underpants, and Sulu the Bionic Hamster battle the three Ridiculous Robo-Boogers in an attempt to turn the Bionic Booger Boy back into Melvin Sneedly.

Only Captain Underpants can stop the three evil space aliens who have invaded Jerome Horwitz Elementary School and turned everyone into lunchroom zombie nerds.

When Professor Pippy P. Poopypants comes to Jerome Horwitz Elementary School to teach science, and he goes off the deep end because students make fun of his name, only Captain Underpants can save the school from the professor's perilous plot.