Aware their grandmother is gravely ill, four siblings learn to realize the value of loss, life, and the importance of being able to say goodbye.

Ten-year-old Caitlin, who has Asperger's Syndrome, struggles to understand emotions, show empathy, and make friends at school, while at home she seeks closure by working on a project with her father.

In an attempt to overcome his grief, a boy tries to think of the ten best things about his dead cat.